Ever wondered, if and how you can set a Registry Key via Intune without having to deploy a PowerShell Script? You totally can do this now relatively easy via ADMX Ingestion like described here: Import custom and third party partner ADMX templates in Microsoft Intune | Microsoft Learn
In my example I wanted to set the DPI Scaling fixed to 100% as i wanted to create a Digital Signage Kiosk Client that should not try to automatically detect the Scaling Level.
You can find my example ADMX File on my GitHub: mmeierm/ADMX_Templates: Custom ADMX Template Examples (github.com)
After you uploaded the ADMX Files in Intune, you can simply create a new Configuration Policy (Imported Administrative templates) and set your newly created Settings: